Marie Curie FP7 ITN ECHONET

 

ECHONET was a Marie Curie Initial Training Network (ITN) for early stage researchers (ESRs) and experienced researchers (ERs) funded by the European Commission under the FP7 'People' Programme.

 

The ECHONET ITN started in January 2013 and ended on December 2016. The network provided research and training opportunities for 11 researchers (9 ESRs and 2 ERs) in the field of synthetic chemistry for the preparation of bioactive molecules. The network comprised 8 full partners (6 academic and 2 industrial) and 2 industrial associated partners.

 A full description of the International Training Network ECHONET is given in the ECHONET site (https://sites.google.com/a/sheffield.ac.uk/echonet-itn/). ECHONET offered research training in state-of-the-art chemical synthesis, catalysis, computational chemistry, bioactive molecule design and high throughput library synthesis on both solid phase and flow platforms. Through integration of the complementary, interdisciplinary and intersectorial expertise of the associated partners, and the secondments of researchers to the associated partners, this ITN helped to strengthen Europe’s human resources in the fine chemical, agrochemical and pharmaceutical industries.

The researchers were supervised and mentored by internationally recognised experts and have access to state-of-the-art equipment. Hands-on training were supplemented by formal training courses in relevant and related fields, and a wide variety of complementary training courses, summer school and seminars were provided. The training of researchers benefitted from secondments to industrial partners, gaining exposure to commercial and complementary environments.

 

Overall, the ECHONET project provided our Early Stage Researchers (ESRs) and Experienced Researchers (ERs) with an outstanding training experience, through extensive technical and complementary skills development.

 

The Academic Full Partners were:

University of Sheffield - United Kingdom - Professor Joe Harrity - Network Coordinator

Universidad del Pais Vasco - Spain - Professor Enrique Gómez Bengoa

Karlsruhe institute for Technology - Germany - Professor Stefan Bräse

Università Degli Studi di Firenze - Italy - Professor Ernesto G. Occhiato

Universitat de Barcelona -Spain - Professor Josep Bonjoch

RadboudUniversityNijmegen - Netherlands -Professor Floris Rutjes

 

The Industrial Full Partners were:

Bayer CropScience - Germany - Dr Stephen Lindell

Borochem - France - Dr Alexandre Bouillion

 

The Industrial Associated Partners were:

Peakdale Molecular - United Kingdom - Dr Matt Tozer

Future Chemistry - Netherlands - Dr Pieter Nieuwland

 

As for the ESR enrolled in the Chemical Science PhDcourse of the University of Florence, her research was carried out in the context of the Work Package 4: Heterocycle Ring Functionalisation, in particular in

 

Project 11: Sequential Pd(0)-catalyzed and pericyclic reactions towards new trehalase inhibitors.

 

Briefly, by exploiting Pd-catalyzed coupling and carbonylative reactions of lactam-derived enol phosphates and triflates, it was possible to prepare functionalized N-heterocycle derivatives which were subjected to Lewis acid- or Au-catalyzed Nazarov reactions, and cyclopropanation as well, providing, after functional group manipulation, a novel series of polyhydroxylated polycyclic N-heterocycles. The ESR had a secondment at Karlsruhe Institute for Technology and one at Peakdale.